).Ĭopyright 2006 Massachusetts Medical Society. (Current Controlled Trials number, ISRCTN93793971. In patients with operable gastric or lower esophageal adenocarcinomas, a perioperative regimen of ECF decreased tumor size and stage and significantly improved progression-free and overall survival. 23 percent) and of progression-free survival (hazard ratio for progression, 0.66 95 percent confidence interval, 0.53 to 0.81 P<0.001). As compared with the surgery group, the perioperative-chemotherapy group had a higher likelihood of overall survival (hazard ratio for death, 0.75 95 percent confidence interval, 0.60 to 0.93 P=0.009 five-year survival rate, 36 percent vs. With a median follow-up of four years, 149 patients in the perioperative-chemotherapy group and 170 in the surgery group had died. The resected tumors were significantly smaller and less advanced in the perioperative-chemotherapy group. The Park features a picturesque 44 acre lake, hiking trails, a Nature Center with a state-of-the-art Planetarium Theater. Rates of postoperative complications were similar in the perioperative-chemotherapy group and the surgery group (46 percent and 45 percent, respectively), as were the numbers of deaths within 30 days after surgery. The primary end point was overall survival.ĮCF-related adverse effects were similar to those previously reported among patients with advanced gastric cancer. Chemotherapy consisted of three preoperative and three postoperative cycles of intravenous epirubicin (50 mg per square meter of body-surface area) and cisplatin (60 mg per square meter) on day 1, and a continuous intravenous infusion of fluorouracil (200 mg per square meter per day) for 21 days. We randomly assigned patients with resectable adenocarcinoma of the stomach, esophagogastric junction, or lower esophagus to either perioperative chemotherapy and surgery (250 patients) or surgery alone (253 patients). We assessed whether the addition of a perioperative regimen of ECF to surgery improves outcomes among patients with potentially curable gastric cancer. 360 rotate products using a set of images (normally 18 or 36), the effect creates a smooth spin with motion blur effects, customizable magnifying glasses and 10 other options that you may adjust. It is the ultimate way to inspect a product on a webpage in every detail. This revolutionizes the way organizations conceive, develop and realize new products, delivering competitive edge through innovative customer experiences.A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable locally advanced or metastatic gastric adenocarcinoma. Magic 360 combines 360° spin with image zoom. This enables multiple disciplines to leverage powerful and integrated specialist applications across all phases of the product development process.ĬATIA’s Design, Engineering, Systems Engineering and Construction applications are the heart of Industry Solution Experiences from Dassault Systèmes to address specific industry needs. An Inclusive product development platform that is easily integrated with existing processes & tools.An Instinctive 3DEXPERIENCE, for both experienced and occasional users with world-class 3D modeling and simulation capabilities that optimize the effectiveness of every user.A Social design environment built on a single source of truth and accessed through powerful 3D dashboards that drive business intelligence, real-time concurrent design and collaboration across all stakeholders including mobile workers.Systems architects, engineers, designers, construction professionals and all contributors can define, imagine and shape the connected world.ĬATIA, powered by Dassault Systèmes’ 3DEXPERIENCE platform, delivers: CATIA delivers the unique ability not only to model any product, but to do so in the context of its real-life behavior: design in the age of experience.
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